База тестів крок-1 з патофізіології (пмк-1)

Дата конвертації25.01.2021
Розмір1.62 Mb.
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Test 112

For the past 2 days, a 41-year-old man has had a severe headache, and he now has a temperature of 39.2°C. A lumbar puncture is performed, and the cerebrospinal fluid obtained has a WBC count of 9×109/L with 94% neutrophils and 6% lymphocytes. Which of the following substances is the most likely mediator for the fever observed in this patient?

  1. Bradykinin

  2. Leukotriene B4

  3. Histamine

  4. Myeloperoxidase

  5. Interleukin-1

Test 113

A 6-year-old child has a history of recurrent infections with pyogenic bacteria, including Staphylococcus aureus and Streptococcus pneumonia. The infections are accompanied by a neutrophilic leukocytosis. Microscopic examination of a biopsy specimen obtained from an area of soft tissue necrosis shows microbial organisms, but very few neutrophils. An analysis of neutrophil function shows a defect in rolling. This child's increased susceptibility to infection is most likely caused by a defect in which of the following molecules?

  1. Selectins

  2. Integrins

  3. Leukotriene B4

  4. Complement C3b

  5. NADPH oxidase

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