База тестів крок-1 з патофізіології (пмк-1)
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Test 17 In an experiment, cells are subjected to radiant energy in the form of x-rays. This results in cell injury caused by hydrolysis of water. Which of the following cellular enzymes protects the cells from this type of injury? Phospholipase Glutathione peroxidase Endonuclease Lactate dehydrogenase Protease Test 18 Reperfusion of ischemic tissues, as may occur after therapeutic use of thrombolytic agents, sometimes leads to cell death after the blood flow resumes. The biochemical basis for cell death under these circumstances is most likely which of the following? Reduction in protein synthesis Increased generation of oxygen derived free radicals Increased activity of catalase Reduced oxidative phosphorylation Release of calcium from endoplasmic reticulum Test 19 A nurse of radiological department is exposed to radiation as a result of violation of the rules of safety appliances. In 8 days she develops ulcero-gangrenous stomatitis. The patient’s blood test shows: RBC – 3.2 x 1012/L, reticulocytes – 0.01 %, Hb – 60 g/L, WBC – 2.3 x 109/L, and platelets – 50 x 109/L. Which of the following stages of acute radiation sickness is described? Prodromal Manifest illness stage Latent Pretended well-being stage Outcome Test 20 During nuclear power plant breakdown elimination a firefighter receives 30 Gy dose of ionizing radiation. Which of the following organs is damaged most? Lung Bone marrow Gut Skin Brain Test 21 During nuclear power plant breakdown elimination a 24-year old firefighter receives 7 Gy dose of ionizing radiation. Which of the following findings is likely to be in his blood on the 10th day after the accident? Leukemoid leaction Lympocytosis Monocytosis Neutrophilia Agranulocytosis Test 22 A worker is exposed to ionizing radiation due to an accident at a nuclear power plant. On his examination agranulocytosis is revealed. Which of the following mechanisms is responsible this phenomenon? Increased entrance of agranulocytes from the bone marrow Loss of granulocytes via hemorrhage Increased migration of granulocytes to tissues Increased destruction of granulocytes in blood Oppression of leucopoiesis Test 23 Hemorrhagic syndrome develops in a 35-year old man who took part in nuclear power plant breakdown elimination. Which of the following mechanisms is likely underlines this syndrome? Increased fibrinolysis Decreased synthesis of fibrinogen Hemophilia Thrombocytopenia Thrombocytosis Test 24 During an accident in the radiological department a 40-year old lab technician received 6 Gy dose of ionizing radiation. Which of the following signs or symptoms is likely occurs in the patient in the latent period of acute radiation sickness? Lymphopenia Headache Anemia Vomiting Diarrhea Test 25 A 19-year old firefighter who took part in nuclear power plant breakdown elimination is admitted to hospital because he got 9 Gy dose of ionizing radiation. Which of the following body systems is damaged first? Nerves Cardiovascular Immune Digestive Hemopoietic Test 26 Which of the following processes is considered as a direct effect of ionizing radiation? Inhibition of DNA-synthesis Radiolysis of water Inhibition of antioxydants Interaction between free radicals and enzymes Injury to chromosomes by free radicals Test 27 Radiosensitivity of tissues is determined first of all by which of the following its characteristics: Rate of proliferation Rate of basal metabolism Level of antioxidants Number of mitochondria Rate of functional activity Test 28 A 29-year old firefighter who took part in nuclear power plant breakdown elimination is admitted to hospital because he got 7 Gy dose of radiation. Which of the following findings in his blood is likely to be in 18 hours after an accident? Agranulocytosis Thrombocytopenia Anemia Leukocytosis Leukopenia Test 29 A worker who took part in nuclear power plant breakdown elimination consults a doctor about marked weakness, increase in body temperature to 37,8oC, multiple punctate hemorrhages on his skin and mucous membranes, diarrhea. The patient’s blood test shows the following: ESR – 25 mm/h, RBC – 2,4x1012/L, WBC - 2,2x109/L, platelets – 70x103/L. Which of the following periods of acute radiation sickness is this picture typical of? Manifest illness stage Prodromal Latent Pretended well-being stage Primary reactions period Test 30 A patient with acute radiation sickness complains of splitting headache, marked weakness, difficulty in swallowing of food. On his examination gingivitis, necrotic angina, multiple skin hemorrhages and blood in urine and feces are revealed. Which of the following body tissues is damaged most? Bone Glandular epithelium Neural Lymphoid Hemopoetic Test 31 In an experiment a rabbit was exposed to radiation and it received 5 Gy dose. Which of the following mechanisms are involved in cell damage primarly? Acidosis Hypoxia Lipid peroxidation Electrolyte dysbalance Apoptosis Test 32 A 34-year old firefighter develops marked weakness, tachycardia, decreased blood pressure, abdominal pain, vomiting. On his examination hypovolemia and blood in feces are reveals. Two weeks ago he received 30 Gy dose of radiation. Which of the following forms of acute radiation sickness are these signs and symptoms typical of? Intestinal Bone marrow Cerebral Hemorrhagic Neurological Test 33 A white rat is exposed to ionizing radiation and it receives 5 Gy dose. Which of the following findings in its blood can be expected in 10 hours after the exposure? Leukopenia Pancytopenia Thrombocytopenia Neutrophil leukocytosis Agranulocytosis Test 34 Collapse, anuria, loss of consciousness, convulsions and paralysis occur in a firefighter who received radiation in dose of 80 Gy. Which of the following forms of radiation sickness develops in the patient? Cerebral Bone marrow Toxemic Intestinal Chronic Скачати 1.62 Mb. Поділіться з Вашими друзьями:
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