Pathophysiology of the endocrine system Parodontitis is treated with calcium preparations and a hormone that stimulates tooth mineralization and inhibits tissue resorption. What hormone is it?
A 41-year-old male patient has a history of recurrent attacks of heartbeats (paroxysms), profuse sweating, and headaches. Examination revealed hypertension, hyperglycemia, increased basal metabolic rate, and tachycardia. These clinical presentations are typical for the following adrenal pathology:
Hyperfunction of the medulla
Hypofunction of the medulla
Hyperfunction of the adrenal cortex
Hypofunction of the adrenal cortex
In the course of an experiment adenohypophysis of an animal has been removed. The resulting atrophy of thyroid gland and adrenal cortex has been caused by deficiency of the following hormone:
A patient with signs of osteoporosis and urolithiasis has been admitted to the endocrinology department. Blood test has revealed hypercalcemia and hypophosphatemia. These changes are associated with abnormal synthesis of the following hormone:
A child has abnormal formation of tooth enamel and dentin as a result of low concentration of calcium ions in blood. Such abnormalities might be caused by deficiency of the following hormone:
Atria of an experimental animal were superdistended by blood that resulted in decreased reabsorption of Na+ and water in renal tubules. This can be explained by the influence of the following factor upon kidneys:
A 44 year old woman complains of general weakness, heart pain, significant increase of body weight. Objectively: moon face, hirsutism, AP is 165/100 mm Hg, height - 164 cm, weight - 103 kg; the fat is mostly accumulated on her neck, thoracic girdle, belly. What is the main pathogenetic mechanism of obesity?
Increased production of glucocorticoids
Reduced production of thyroid hormones
Increased insulin production
Reduced glucagon production
Increased mineralocorticoid production
Examination of a 42 year old patient revealed a tumour of adenohypophysis. Objectively: the patient’s weight is 117 kg, he has moon-like hyperemic face, redblue striae of skin distension on his belly. Osteoporosis and muscle dystrophy are present. AP is 210/140 mm Hg. What is the most probable diagnosis?
A 38-year-old female patient complains of general weakness, cardiac pain, increased appetite, no menstruation. Objectively: the height is 166 cm, weight 108 kg, the patient has moon-shaped face, subcutaneous fat is deposited mainly in the upper body, torso and hips. There are also blood-red streaks. Ps- 62/min, AP-160/105 mm Hg. Which of the following diseases is the described pattern of obesity most typical for?
Cushing pituitary basophilism
A 19-year-old male was found to have an elevated level of potassium in the secondary urine. These changes might have been caused by the increase in the following hormone level:
The patient with complaints of permanent thirst applied to the doctor.
Hyperglycemia, polyuria and increased concentration of 17-ketosteroids in the urine were revealed. What disease is the most likely?
Insulin-dependent diabetes mellitus
Type I glycogenosis
A 20 year old patient complains of morbid thirst and huperdiuresis (up to 10 l daily). Glucose concentration in blood is normal but it is absent in urine. The patient has been diagnosed with diabetes insipidus. What hormonal drug is the most appropriate for management of this disorder?
A 30-year-old female exhibits signs of virilism (growth of body hair, balding temples, menstrual disorders). This condition can be caused by the overproduction of the following hormone:
A 46-year-old patient suffering from the diffuse toxic goiter underwent resection of the thyroid gland. After the surgery the patient presents with appetite loss, dyspepsia, increased neuromuscular excitement. The body weight remained unchanged. Body temperature is normal. Which of the following has caused such a condition in this patient?
Reduced production of parathormone
Increased production of thyroxin
Increased production of calcitonin
Increased production of thyroliberin
Reduced production of thyroxin
The secretion of which hypophysial hormones will be inhibited after taking the oral contraceptives containing sex hormones?
16. A female patient with bronchial asthma had taken prednisolone tablets (1 tablet 3 times a day) for 2 months. Due to a significant improvement of her condition the patient suddenly stopped taking it. What complication is likely to develop in this case?
17. A patient complains of polyuria (7 liters per day) and polydipsia. Examination reveals no disorders of carbohydrate metabolism. These abnormalities might be caused by the dysfunction of the following endocrine gland:
Islets of Langerhans (pancreatic islets)
18. For people adapted to high external temperatures profuse sweating is not accompanied by loss of large volumes of sodium chloride. This is caused by the effect the following hormone has on perspiratory glands:
19. On examination the patient presents with hirsutism, moon-shaped face, stretch marks on the abdomen. BP is 190/100 mm Hg, blood glucose is 17,6 mmol/l. What pathology is such clinical presentation characteristic of?