База тестів крок-1 з патофізіології (пмк-1)


A. Carbohydrate starvation of The brain B



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A. Carbohydrate starvation of The brain

B. Increased glycogenolysis

C. Increased ketogenesis

D. Increased lipogenesis

E. Decreased glyconeogenesis


Protein and lipidic metabolic disorders.

  1. A patient with homogentisuria has signs of arthritis, ochronosis. In this case, the pain in the joints is associated with the deposition of:

    1. Homogentisates

    2. Urates

    3. Phosphates

    4. Oxalates

    5. Carbonates



  1. A patient has been diagnosed with alkaptonuria. Choose an enzyme whose deficiency can be the reason for this pathology:

    1. Homogentisic acid oxidase

    2. Phenylalanine hydroxylase

    3. Glutamate dehydrogenase

    4. Pyruvate dehydrogenase

    5. Dioxyphenylalanine decarboxylase



  1. In case of alkaptonuria, homogentisic acid is excreted in urine in large amounts. The development of this disease is associated with a disorder of metabolism of the following amino acid:

    1. Tyrosine

    2. Phenylalanine

    3. Alanine

    4. Methionine

    5. Asparagine



  1. A 2 year old child with mental and physical retardation has been delivered to a hospital. He presents with frequent vomiting after having meals. There is phenylpyruvic acid in urine. Which metabolism abnormality is the reason for this pathology?



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