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Pathophysiology of the endocrine system



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Дата конвертації25.01.2021
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Pathophysiology of the endocrine system

#Adenoma of glomerular zone of the cortex of the adrenal glands was diagnosed in the patient. Thereof the initial hyperaldosteronism (Konn’s desease) has developed. The balance of what ion is changed in this case?

-Calcium

-Chlor


-Magnesium

+Sodium


-Iron

#The patient suffers from chronic failure of the adrenal glands cortex – Addison’s disease. Lack of wich hormone is observed in this case?

-Vasopressin

-Insulin

-Epinephrine

-Thyroxine

+Aldosterone

#In 1-2 hours after extraction of the parathyroid glands, the dog developed such symptoms as - weakness, thirst, sudden increase of nervimuscular excitability with development of convulsions. What kind of electrolyte dysbalance takes its place in this case?

-Hypermagniemia

-Hypercalciemia

-Hypomagniemia

+Hypocalciemia -Hyponatriemia

#The patient, 28 years old, complains of weakness mental and physical tiredness, dyspepsia. Tuberculine test was positive, hypoglycemia, arterial pressure - 90/60 mm Hg, hyponatriemia, and skin overpigmentation was also founded. In which the pathology of epinephral glands such phenomenas are observed?

+Addison’s disease

-Itsenko-Cushing syndrome

-Acute failure of the cortex of the epinephral glands

-Adrenogenital syndrome

-Konn’s syndrome

#The woman, 44 years old, complains of general weakness, obesity of the upper part of the body, appearance of hair on the face, menses discontinuance and hyperglycemia. Arterial pressure is 165/100 mm Hg. Which parameter detection will allow distinguishing Itsenko-Cushing disease from Icenco-Cushing syndrome caused by adenoma of the epinephral glands?

-Level of androgens in blood plasma

-Level of hydrocortisone in plasma

-Level 17-oxysteroids in urine

+Level of corticotropin in blood plasma

-Amount of eosinophiles in blood

#Some months after delivery of a baby, the woman developed loss of hair and teeth, body mass, she became very flaccid. Later the arterial pressure, body temperature, concentration of glucose, somatotropin and corticotrophin in blood reduced. What pathology of the pituitary gland is observed?

-Diabetes

-Pituitary nanism

-Acromegalia

-Itsenko-Cushing disease

+Panhypopituitarism

#The child, 10 years old, has hyperergical form of rheumatoid arthritis with a pronounced pain syndrome which can’t be treated by nonsteroid anti-inflammatory drugs. Therefore it was necessary to use anti-inflammatory hormones. What hormone has anti-inflammatory effect? -Epinephrine

+Hydrocortisone

-Somatotropnin

-Testosterone

-Insulin

#The woman, 53 years old, height -163 cm, weight - 92 kg, demonstrates edema of the face and upper extremities. After pressing on the skin a pit does not occur, skin is dry and yellowish. Arterial pressure - 90/60 mm Hg. Pulsrate - 56. Which endocrine gland insufficiency such symptoms be related to?

-Neurohypophysis

-Cortex of the epinephral gland

+Thyroid gland

-Ovaries

-Parathyroid glands

#The woman, 26 years old, complains of weakness, loss of weight (18 kg), absence of menses. She is ill during one year after difficult delivery. Objectively: body height 168 cm, weight 50 kg, hypoplasia of the mammas, hypoglycemia and atrophy of the muscles. Failure of which gland the loss is of body mass connected with?

-Thyroid -Sexual glands

-Cortex of the epinephral glands

+Adenohypophysis

-Parathyroid

#The patient, 50 years old, had encephalitis. Later diuresis increased up to 12 L a day. The level of glucose in blood was 4.1 mmol/L. Lack of what hormone can this condition be connected with? -Aldosterone

-Glucagon

-Insulin -Hydrocortisone

+Vasopressin

#The patient has continuously increased body temperature, tachycardia, emotional lability and tremor. Which hormone concentration can change cause this condition?

-Vasopressinum

+Thyroxine

-Testosterone

-Aldosterone

-Insulin

#The woman, 44 years, old complains of weakness, pain in the heart region, significant weight gain. Objectively: lunar face, arterial pressure - 165/100 mm Hg. Body height - 164 cm, weight - 103 kg, fatty deposits predominantly on the of face, neck, shoulders, abdomen. What is the cause of these development signs?

-Deficiency of thyroid hormones

+Excess of glucocorticoids

-Excess of insulin

-Deficiency of glucagon

-Excess of mineralocorticoids

#The patient, 50 years old, complains of thirst, pronounced polyuria, taking plenty of water. Glucose of blood – 4.8 mmol/L. In urine is glucose and acetone are absent; urine colourless, relative density 1002-1004. What caused polyuria?

-Thyrotoxicosis

-Hypothyroidism

-Lack of insulin -Aldosteronism

+Lack of vasopressin

#The patient with hyperthyroidism complains of growing thin, tachycardia, tremor of fingers, fiver. Based metabolism is 40% increased. What is the cause of basal metabolism increase? -Intensifying of glycogenesis

-Activation of glyconeogenesis

+Activation of oxidative processes

-Intensifying of lipogenesis -Depressing of proteolysis

#Clinical examination of the woman revealed tachycardia, weight loss, tremor, increased sweat. What endocrine pathology can cause it?

-Hypergonadism

-Hypothyroidism

+Hyperthyroidism

-Hypogonadism

-Hypoaldosteronism



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