#The scleras and skin of the 20-year-old patient periodically become yellow; he feels sickness. Diagnosis: Minkovski-Shoffar desease. What are the typical findings of the blood test?
#The boy, 3 years old, with pronounced hemorrhagic syndrome doesn’t have antihemophilic globulin A (the factor VIII) in blood plasma. What phase of hemostasis is primarily broken in such a case?
-Retraction of bloody clot
-The external mechanism of prothrombinase activation
-Transformation of thrombinogen to thrombin
-Transformation of fibrinogen to fibrin
+The intrinsic mechanism of prothrombinase activation
#The child, 1.5 years old, was hospitalized with symptoms of nitrate poisoning: persistant cyanosis, dyspnoe, convultions. Synthesis of hemoglobin what form is the cause of these symptoms?
#The child, 3 years old, was hospitalized with a hemoglobinopathy (sickle cell anemia). What amino- acid replaced glutamin acid in a β-chain of haemoglobin S?
#The patient who has arrived from Tunis revealed α-thalassemia with hemolysis of erythrocytes and icterus. Presence of what cells in blood is typical for this illness?
#The patient, 36 years old, with respiratory viral infection was treated with sulphanilamide drugs. Blood test findings revealed hyporegenerative normochrome anemia, leukopenia, and thrombocytopenia, in bone nerrow - decreased amount of myelokariocytes. What anemia is it? -Posthemorrhagic
Deficient - В12 and Folic
-Iron – deficient
#Microcythemia, poikilocytosis, and anulocytosis are found in the patient’s blood smear, anulocytose. What anemia are these changes characteristic for?
Deficient – В12 and Folic
-Sickle cell anemia
+Iron - deficient
#A resection of the stomach was perfomed to a patient. Then he developed В12-deficient anemia. What color index is characteristic for this anemia?
#The test findings of peripheric blood of the patient 42, years old, are: hemoglobin - 80 g/L, erythrocytes - 3,2 ·1012/L, leucocytes - 25 ·109/L, the leukocytic formula: basophils - 5%, eosinophils - 9%, myeloblasts - 3%, promyelocytes - 8%; neutrophils: myelocytes - 11%, metamyelocytes - 22%, stab neutrophile - 17%, segmentinuclei - 19%, lymphocytes - 3%, monocytes - 3%. What kind of pathology of blood is it?
#The woman complains of headache, giddiness, dispnoe while an exercise stress. During last 3 years extensive menstrual bleedings were marked. Results of visual inspection: the patient has normal body type, skin is pale and dry. Analysis of blood: hemoglobin - 90 g/L, erythrocytes - 3,7 ·1012/L, a color index - 0,7, SSE - 20 mm/h, significant hypochromia of erythrocytes, anisocytosis, poikilocytosis. What type of anemia is it?
В12 and Folic - deficient
#The woman is at the 6-th month of pregnancy. Blood findings: the amount of erythrocytes and a hemoglobin is reduced, color index - 1,4, megalocytes, oxyfile megaloblasts. What type of anemia is it?
#Woman, 34 years old, with dignosed hereditary hemolytic microspherocytar anemia (Minovski-Shoffar desease). What is the cause of hemolysis of erythrocytes in this case? -Fermentopathia
#Blood examination revealed - leukocytosis, lymphocytosis, Botkin-Gumperht shades, and anemia. What disease can it be?
+Chronic lymphoid leukosis
-Infectious mononucleosis -Acute leukosis
#Blood examination revealed thrombocytopenia as a complication of autoimmune process.
What is the mechanism of thrombocytopenia onset ih this case?
-Disturbance of regulation of thrombocytopoesis
-Decrease of production of thrombocytes
-Redistribution of thrombocytes
+Increased distruction of thrombocytes
-Increased consumption of thrombocytes
#The man, 40 years old, was established the diagnosis: sickle cell anemia. What is the mechanism of decreasing of erythrocytes count in blood?
-Inhibition of erythropoesis
-Disturbance of DNA synthesis
#A clinical observation of a man, 50 years old, revealed the decreased amount of erythrocytes in blood and increased level of free hemoglobin in blood plasma (hemoglobinemia). The color index-0,85. What kind of anemia is the most probable in this case?
#The patient with a chronic diffuse glomerulonephritis suffers from anemia. What is the pathogenesis of this anemia?
-Presence of antibodies to cells of peripheric blood
-Increased deficiency of internal Castle factor
-Hemolysis of erythrocytes
+Diminished production of erytropoethin
#Degenerative and regenerative forms of erythrocytes were found in a peripheric blood of the patient with toxic hemolytic anemia. What cells are referred the regenerative forms?
#The erythrocytes of the patient with hypochromic anemia contain 45% Hb S and 55% Hb А1. What form of anemia is it?
#The woman, 40 years old, regularly used aspirin. Hemorrhages occured, there was detected disturbance of functional activity of thrombocytes. Depression of what enzyme activity may be trombocytotopathy caused by?
+Cyclooxygenase -Na+/K+-ATP- ase
#A woman, 58 years old, complains of tiredness, sleepiness, dyspnoe while fast walking. Analysis of blood: erythrocytes - 4·1012/L, hemoglobin - 92 g/L, color index - 0,6, plenty of anulocytes and microcytes. What anemia is it?
#Iron-deficiency anemia has been revealed in a patient. Atrophic and dystrophic processes in the alimentary canal (glossitis, gingivitis, caries, esophagitis) can be consequences of a long course of this disease. What is the cause of such changes associated with this anemia?