База тестів крок-1 з патофізіології (пмк-1)



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ЛИХОРАДКА
Test 159

In experiment a rat is injected with Pyrogenal to produce fever. Which of the following mechanisms triggers an increase of body temperature in the rat?



  1. Activation of shivering thermogenesis

  2. Activation of non-shivering termogenesis

  3. Excessive heat production

  4. Uncoupling of oxidative phosphorylation

  5. Upward shift in the temperature regulatory set-point


Test 160

Treatment with Aspirin causes patient’s body temperature to decrease quickly. Which of the following mechanisms is responsible for this effect of Aspirin?



  1. Inhibition of IgE synthesis

  2. Inhibition of leukotriens synthesis

  3. Inhibition of cyclooxygenase

  4. Inhibition of lipooxygenase

  5. Inhibition of histamine release


Test 161

A 2-year child with pneumonia develops an increase in body temperature. Which of the following substance causes fever in the patient?



  1. Interleukin-1

  2. Complement

  3. Histamin

  4. Bradykinin

  5. Interleukin-2


Test 162

Pallor of the skin, gooseflesh, and increased oxygen consumption is observed in a patient with fever. What ratio between heat production and heat loss is the fever described period characterized?



  1. Heat production exceeds heat loss

  2. Increased heat production with no change in heat loss

  3. Heat production equals heat loss

  4. Decreasd heat loss with no change in heat production

  5. Heat loss exceeds heat production


Test 163

After drinking a 42- year- old man develops acute pancreatitis. By a night his condition deteriorates: body temperature rises to 40 °C. Further his temperature daily fluctuations are 4ºC. Abscess formation is suspected.Which of the following fever patterns most likely confirms an abscess formation?



  1. Continuos

  2. Remittent

  3. Atypical

  4. Hectica

  5. Ephemera


Test 164

A 19-year-old man develops fever. In morning his body temperature suddenly increases to 40ºС and retunes to its normal level in 4 hours. These paroxysmal periods are followed by apyretic periods and repeat each two days. Which of the following fever patterns does the patient have?



  1. Ephemera

  2. Remittent

  3. Recurrent

  4. Continuos

  5. Intermittent


Test 165

On an examination of a 6-year girl the following signs are revealed: her body temperature is 37, 2ºС; her skin is hyperemic and moist by touch; polyuria is present. Which of the following fever stages does the patient develop?



  1. Incrementi

  2. Decrementi

  3. Fastigii

  4. Prodromal

  5. Of marked manifestations


Test 166

On an examination of a 16-year old boy with pneumonia the following clinical signs are found out: his skin is pink, dry and warm by touch, his heart rate is 92 per minute, his respiratory rate is 22 per minute, body temperature is 39, 2ºС. What is the ratio between heat production and heat loss at the fever stage described?



  1. Heat production equals heat loss

  2. Heat production is lower than heat loss

  3. Decreased heat loss with no change in heat production

  4. Increased heat production with no change in heat loss.

  5. Heat production exceeds heat loss


Test 167

In patients with infectious deceases the pattern of temperature changes may occasionally hint at the diagnosis. Which of the following diseases does the oscillating (wavy) type of fever curve correspond to?



  1. Diphtheria

  2. Brucellosis

  3. Influenza

  4. Smallpox

  5. Infectious hepatitis

Test 168

A 30-year old man working at high ambient temperature develops a dramatic increase in his body temperature, headache, tachycardia and a loss of consciousness. Which of the following disorders of thermoregulation is responsible for these signs and symptoms?



  1. An increase in the temperature regulatory set-point

  2. Excessive heat production

  3. Insufficient thermoregulation

  4. Uncoupling of oxidative phosphorylation

  5. A decrease in the temperature regulatory set-point


Test 169

Within a week a patient’ body temperature is kept at 39 ºC level. The difference between his morning and evening temperature does not exceed 1 ºC. Which of the following types of fever curves does he have?



  1. Continuos

  2. Remittent

  3. Intermittent

  4. Hectica

  5. Ephemera



Test 170

A patient with pneumonia develops an increase in the body temperature. Determine the correct sequence of fever stages:



  1. Incrementi, fastigii, decrementi

  2. Incrementi, decrementi, fastigii

  3. Fastigii, decrementi, incrementi

  4. Fastigii, incrementi, decrementi

  5. Decrementi, fastigii, incrementi


Test 171

A 15-year old boy suffers from pneumonia. Within a week a patient’ body temperature is kept at the levels of 38,3-38,5 ºC. Such kind of fever can be considered to:



  1. Febrile

  2. Hyperpyretic

  3. Pyretic

  4. Subfebrile


Test 172

A 35-year old man suffers from the maxilla osteomyelitis. Every day his body temperature rises to 40 ºC and is kept at this level within 5-6 hours after that it drops to 36,0 ºC. Which of the following types of fever curves does he have?



  1. Continua

  2. Intermittent

  3. Remittent

  4. Reccurens

  5. Atypical


Test 173

A 14-year old boy develops uncontrollable shivering for an hour, followed by a rapid spike in temperature (as high as 41 ºC) which lasts six hours. Then, just as suddenly, the patient begins to sweat profusely, which quickly brings down the fever. Which of the following diseases is characterized by the described type of fever?



  1. Tuberculosis

  2. Influenza

  3. Peritonitis

  4. Brucellosis

  5. Malaria



Test 174

A 49-year old woman suffering from pneumonia develops fever. It is known that fever occurs due to endogenous pyrogens synthesis. Which of the following cells are involved in this process?



  1. Eosinophils

  2. Platelets

  3. Mast cells

  4. Macrophages

  5. Dendritic cells




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