База тестів крок-1 з патофізіології (пмк-1)



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Test 144

After car accident a 60 -year old man is admitted to hospital by an ambulance. He is unconscious, his skin is pale, and his pulse and respiratory rate are increased. His blood test shows: RBC - 2, 52*1012/L, hemoglobin – 72 g/L, pO2 - 95 mmHg. Which of the following types of hypoxia does the patient have?



  1. Respiratory

  2. Hypoxic

  3. Hemic

  4. Circulatory

  5. Tissue


Test 145

Hypercapnia, hypoxemia, and respiratory acidosis develop in a 42-year-old man after a bronchial asthma attack. Which of the following types of hypoxia does the patient have?



  1. Hypoxic

  2. Circulatory

  3. Anemic

  4. Tissue

  5. Histotoxic


Test 146

A 28- year-old man complains of weakness and dyspnea during walking. On his examination the following changes in blood gases contents are identified: an increase of arterio-venous oxygen difference, hypoxia is diagnosed. Which of the following disorders is likely to be the cause of the hypoxia?



  1. Hypoxemia

  2. Anemia

  3. Respiratory failure

  4. Cardiac failure

  5. Poisoning with carbon monoxide


Test 147

Several employees of a chemical plant are admitted to a hospital after accident at the plant. All patients complain of weakness, headache, dizziness, nausea, vomiting. Poisoning with nitrocompounds is suspected. Which of the following processes underlines hypoxia developed in the patients?



  1. Inhibition of dehydrogenases

  2. Inhibition of cytochrome oxidase

  3. Decrease of function of flavine enzymes

  4. Formation of methemoglobin

  5. Formation of carboxyhemoglobin


Test 148

16-year old girl is admitted to hospital with cyanide poisoning. Her blood analysis shows decreased arterio-venous oxygen difference. Which of the following types of hypoxia does the patient have?



  1. Tissue

  2. Hypoxic

  3. Circulatory

  4. Anemic

  5. Respiratory


Test 149

A 70- year old man suffers from chronic heart failure. On his examination cyanosis, dyspnea and edema of lower extremities are revealed. Which of the following types of hypoxia does the patient have?



  1. Anemic

  2. Respiratory

  3. Circulatory stagnant

  4. Circulatory ischemic

  5. Histotoxic


Test 150

It is known that persons constantly living at high altitudes develop some adaptive reactions. Which of the following changes can be referred to adaptive one?



  1. An increase in RBCs

  2. Leukocytosis

  3. Hyperoxia

  4. Respiratory alkalosis

  5. Megaloblastic type of erythropoiesis


Test 151

At a post-mortal examination it is established that a 23-year-old girl death results from cyanide poisoning. A disorder of which of the following processes is most likely to be the cause of her death?



  1. Tissue supply with oxygen

  2. Tissue respiration

  3. Hemoglobin synthesis

  4. Lung ventilation

  5. Hemoglobin saturation


Test 152

Increased number of erythrocytes is revealed in the blood of people living in the mountains at altitude of 4000 m. Which of the following mechanisms is responsible for this phenomenon?



  1. Increased vitamin B12 synthesis

  2. Blood concentration

  3. Release of RBCs from their depots

  4. Increased erythropoietin synthesis

  5. A decrease in the circulating blood volume


Test 153

A 57- year old man fell asleep inside his car with the engine running and died from carbon monoxide poisoning. Which of the following kinds of hemoglobin is likely to be the cause of his death?



  1. Carbhemoglobin

  2. Methemoglobin

  3. Carboxyhemoglobin

  4. Desoxyhemoglobin

  5. Oxyhemoglobin


Test 154

A 29-year-old man with carbon monoxide poisoning is admitted to a hospital. He has signs of severe hypoxia. Which of the following substances is formed due to carbon monoxide poisoning?



  1. Methemoglobin

  2. Carboxyhemoglobin

  3. Carbhemoglobin

  4. Sulfhemoglobin

  5. Oxyhemoglobin


Test 155

At altitude of 3500 m most of unacclimatized individuals develop dyspnea, dizziness and palpitation. Which of the following types of hypoxia underlines these symptoms?



  1. Circulatory

  2. Hypoxic

  3. Respiratory

  4. Hemic

  5. Tissue


Test 156

Environmental pollution with nitrocompounds results from an accident on a chemical plant. People living in the affected region consult a doctor about weakness, headache, nausea and vomiting. Poisoning with nitrocompounds is suspected. Which of the following processes underlines hypoxia developed in the patients?



  1. Cytochromoxidase inactivation

  2. Dehydrogenase suppression

  3. Carboxyhemoglobin formation

  4. Decreased erythropoiesis

  5. Methemoglobin formation


Test 157

Total respiratory insufficiency is revealed in a 35-year old woman suffering from bronchial asthma. Which of the following mechanisms is responsible for hypoxia in this patient?



  1. Decreased lung perfusion

  2. Decreased oxygen diffusion

  3. Decreased lung ventilation

  4. Suppression of the respiratory center

  5. Weakness of respiratory muscle

Test 158

A 4-year-old boy with nitrite poisoning is admitted to a hospital. Which of the following mechanisms is responsible for hypoxia in this patient?



  1. Methemoglobin formation

  2. Inhibition of dehydrogenase

  3. Inhibition of cytochrome oxidase

  4. Carboxyhemoglobin formation

  5. Deficiency of riboflavin




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