The surgical wound following suturing of the incision site for a cholecystectomy in the right upper abdominal quadrant will have ingrowth of new capillaries. The major factor that is elaborated by macrophages at the wound site to stimulate this capillary proliferation is:
Platelet-derived growth factor
Fibroblast growth factor
Epidermal growth factor
A 4-year-old male is evaluated in your clinic for recurrent skin and respiratory infections. He has light skin and silvery hair. Horizontal nystagmus is present on eye examination. Peripheral blood smear demonstrates giant cytoplasmic granules in neutrophils and monocytes. The patient most likely suffers from which of the following disorders?